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If users want to run testosterone during a cutting cycle, but with minimal water weight, an anti-estrogen such as anastrozole or letrozole can be takento prevent the formation of a "negative water balance syndrome" or "water-weight syndrome". A well-designed cut cycle involves a gradual increase in testosterone and a gradual decrease in dihydrotestosteron (DHT). DHT is a male sex hormone that's created in small amounts by the body's cells. It's produced by the body's own enzyme aromatase and causes an increase in estrogen. Estrogen regulates a number of body tissues including the testicles and uterus in men. Testosterone is made primarily in the liver and prostate glands in men. Although dihydrotestosterone is not a steroid hormone, it does enhance a testosterone-driven response in the body. Testosterone and estrogen together affect male sex characteristics including growth and development of genitalia, voice, muscle tone and fat distribution. Estrogen also modulates female sexual characteristics such as the menstrual cycle, body hair and menstrual flow. Estrogens and DHT are the two main female sex hormones that affect a variety of functions in humans. Estrogen is also involved in the process of puberty, sex organ formation during pregnancy, and male and female sexual differentiation. Male sex characteristics DHT is one of the main male sex characteristics that's influenced by estrogen. Male sex characteristics include testicles, penis and testicular size. Testosterone is used most strongly for males by increasing testosterone production in the testicles and penis and reducing testosterone-induced effects. Testosterone also increases male muscle mass and strength. Dihydrotestosterone is an anti-androgen and blocks production of DHT. If enough testosterone is released and sustained, the body accumulates dihydrotestosteron (DHT). A dihydrotestosteron induced positive water balance syndrome or water-weight syndrome can result if the body's body fat is above the recommended ranges in a cutting cycle (the range for lean body mass is from 12 to 20% and the range for fat mass is from 60 to 80%). Because dihydrotestosteron levels can vary from person to person, dihydrotestosteron is used with an anti-estrogen such as anastrozole or letrozole to prevent the formation of these negative water balance syndrome. Water balance syndrome will occur at body fat levels that can cause an increased risk of having a heart attack, stroke or other cardiovascular problems. Similar articles: